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"Although birth defects were not observed in rat fetuses exposed to high levels of hydroquinone, we don't have data in humans showing that it is demonstrably safe to use in pregnancy." Thankfully, alternatives exist to keep melasma and post-inflammatory hyperpigmentation at bay
(2019) 26:623633.e9
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162 In addition, activated notch may affect islet architecture through Ephrin A5 (EFNA5) which is increased in T2D 163 (Fig
Nevertheless, the study fails to clarify differences in serum PCS levels among PBC patients at different disease stages, uses non-human primary Kupffer cells in vitro , and does not evaluate the safety threshold for clinical PCS supplementation, which limits its therapeutic translation
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